Overview

S.E.M.I. – Side Effects May Include... is a cooperative online game developed and published by Two Horn Unicorn. Players step into the shoes of patients attempting to escape a special clinic. This surreal third-person platformer throws you and up to three friends into a chaotic environment where teamwork is paramount for survival.

Highlights

  • Cooperative Escape: Team up with friends to navigate a challenging clinic environment, facing off against staff and other patients.
  • Surreal Platforming Challenges: Expect brutal platforming sections, deadly traps, and intricate puzzles that will test your coordination and problem-solving skills.
  • Dynamic Gameplay: Encounter unexpected situations, utilize side-effect pills, and engage in brawls as you strive for freedom.

Who It's For

This game is perfect for players who enjoy cooperative experiences and don't shy away from a challenge. If you and your friends love surreal settings, physics-based gameplay, and the thrill of overcoming difficult obstacles together, S.E.M.I. should be on your radar. It's designed for those who appreciate a good laugh amidst intense, coordinated gameplay.

Game Info

Developed by Two Horn Unicorn, S.E.M.I. – Side Effects May Include... offers both single-player and online co-op modes for up to 4 players. The game features character customization, adding a personal touch to your escapees. With a release date of January 23, 2026, it promises a unique blend of platforming, physics puzzles, and cooperative chaos. The game is available in multiple languages, including English, Russian, French, German, Spanish, Simplified Chinese, Arabic, Japanese, and Korean.